Maral Aminpour






        Doctor of Philosophy in Physics
        University of Central Florida, Orlando, FL, USA

        Master of Science in Physics
        University of Central Florida, Orlando, FL, USA

        Bachelor of Science in Physics
        University of Tehran, Tehran, Iran





   My research interest is mainly in Computational Biophysics. At Pharmamatrix group, I am currently focusing on conducting computer-aided drug discovery studies to facilitate the design and discovery of new personalized therapeutic solutions (precision medicine) for cancer chemotherapy exploiting the tubulin mutations and isotype-specific effects. I am also involved in different target-based drug discovery projects based on the “lock and key” model. I employ molecular dynamics, docking and virtual screening methods to estimate the energetically favourable binding modes and affinities of molecular drugs to biological targets that are known to be critical in human cancer such as tubulin or tubulin associated motor proteins. 

   In addition, I am interested in modelling of the interfaces of biological systems with materials and design of biomaterials and biomimetic systems with nanobiotechnology applications. 




  1. H. Hoi, Y. He, S. Abraham, M. Aminpour, and C. Montemagno, “Immobilization of membrane protein on solid support using functionalized β-sheet peptides with click chemistry,” Chemical Communications 2018, 54, 1889-1892.
  2. S. Cetinel, W. Shen, M. Aminpour, P. Bhomkar, F. Wang, E. Rafie Borujeny, K. Sharma, N. Nayebi, C. Montemagno, “Biomining of MoS2 with peptide-based smart biomaterials,” Scientific Reports 2018, volume 8, Article number: 3374.
  3. A. S. Mathews, V. Semenchenko, M. Aminpour, and C. Montemagno, “Tagging of recombinant terminal deoxynucleotidyl transferase enzyme for template independent photo initiated oligonucleotide synthesis” (to be submitted to Nucleic Acids Research).
  4. M. Aminpour, J. Stys, H. Hoi, Carlo Montemagno, “All-atom molecular dynamics simulations of a membrane protein stabilizing β-sheet” (to be submitted to Biophysical Journal).
  5. D. T. Restrepo, K. E. Giesler, R. A. Penabe, M. Aminpour, D. Le, T. S. Rahman, and R. G. Blair, “Heterogeneous metal-free hydrogenation over defect-laden hexagonal boron nitride,” ACS Omega 2016, 1 (6), 1343.
  6. H. Jabbari, M. Aminpourand C. Montemagno, “Computational approaches to Nucleic Acid Origami,” ACS Comb. Sci. 2015, 17 (10), 535.
  7. M. Alcántara Ortigoza, M. Aminpourand T. S. Rahman; “Revisiting the surface properties of Mg(0001) thin films and their effect on the adatom binding energy and self-diffusion,” Surface Science 2015, 632, 14-19.
  8. M. Alcántara Ortigoza, M. Aminpourand T. S. Rahman, “Friedel oscillations responsible for stacking fault of adatoms: The case of Mg(0001) and Be(0001),” Phys. Rev. B 2015, 84 91, 115401.
  9. D. Le, D. Sun, W. Lu, M. Aminpour, C. Wang, Q. Ma, T. S. Rahman, and L. Bartels, “Growth of aligned Mo6S6 nanowires on Cu(111),” Surface Science 2013, 611, 1–4.
  10. D. Sun, W. Lu, D. Le, Q. Ma, M. Aminpour, M. Alcántara-Ortigoza, S. Bobek, J. Mann, J. Wyrick, T. S. Rahman, and L. Bartels, “An MoSx structure with high affinity for adsorbate interaction,” Angew. Chem. Int. Ed. 2012, 51, 10284.
  11. D. Le, M. Aminpour, A. Kiejna, and T. S. Rahman, “The role of van der Waals interaction in the tilted binding of amine molecules to the Au(111) surface,” J. Phys.: Condens. Matter 2012, 24, 222001. (IOPSELECT)
  12. M. Aminpour, O. Trushin and T. S. Rahman, “Effect of misfit dislocation on surface diffusion,” Phys. Rev. B 2011, 84, 035455.