Aarat Kalra

 

AaratKalra

 

        Doctor of Philosophy in Physics (Current)
        University of Alberta, Alberta, Canada

        Master of Science in Biology
        McGill Univesity, Montreal, Canada

        Bachelor of Science in Zoology and Chemistry
        Dayalbagh Educational Institute, Agra, India

        Bachelor of Science in Chemistry (Honors)
        Dayalbagh Educational Institute, Agra, India
 

 

Projects:

1. Electrical and spectroscopic characterization of one-dimensional bio-nanowires:
Performing experiments to determine the conductivity of biological nanowires using impedance spectroscopy. Experiments are performed in collaboration with Prof. Karthik Shankar, Principal Investigator of the Nanostructures and Excitonics lab at the University of Alberta. Using electrical and spectroscopic characterization to explore applications of microtubule biophysics in medicine.

2. Precise quantification and analysis of hydration atmosphere in the vicinity of cytoskeletal proteins:
Performing measurements to determine the hydration shell around the microtubule building-block, Tubulin, in different solvents, temperatures and conditions. Using both experimental approaches and simulations to measure the volume of the Tubulin dimer. 

3. Modelling of biological nanowire networks to understand information processing in the cell:
Modelling networks of microtubules in vitro as electrical circuits. 

 

Publications:

  1. Santelices IB, Friesen DE, Bell C, et al. Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions. Sci Rep 2017; 7: 9594.

  2. Harinipriya S, Kalra A, Mishra AK. Physiochemical Characterization of tubulin from Arachis hypogaea. Synth Met 2016; 220: 86–94

  3. Friesen DE, Craddock TJA, Kalra AP, Tuszynski JA. Biological wires, communication systems, and implications for disease. BioSystems 2015; 127: 14–27.